Learn how to write a resignation letter due to family reasons with our stepbystep guide and sample letters. Please accept this letter as a notice of my resignation.Please accept this message as my formal notice of resignation. I am fortunate to have received a long awaited opportunity that I cannot pass up. I am writing to inform you that I have made the difficult decision to resign from my position at Phoenix Realtors. Here are two examples of letters resigning for family or personal reasons. The first is a formal business letter, and the second is an email sample. In the opening paragraph, clearly state that you are resigning from your position. Here are two examples of letters resigning for family or personal reasons. The first is a formal business letter, and the second is an email sample.