In this article, we will discuss how to write a resignation letter as a nurse and provide examples and tips. Termination is the separation of employment from the County of San Bernardino for the reason of voluntary resignation, dismissal, layoff or retirement.It follows the verbal notice you give your supervisor about quitting your job. Why should I write a resignation letter? The best way to leave a job is with grace. Nursing resignation letters should be short, to the point, and professional. Nurses transitioning to a new role require a formal resignation letter. 2. Healthcare professionals who need to document their departure professionally. 3. Need a nursing resignation letter right away? See a sample with tips to help you know what to write and how to make it look professional.