Who should receive my resignation letter? You should give your letter of resignation to your immediate supervisor.Discover how to craft a professional resignation letter due to illness. Use one of our resignation letter templates. The complete guide to writing your resignation letter including expert tips, free copyable samples, and templates. This sample resignation letter is available for use on UpCounsel. Customize and Download this "Employee Resignation Letter for Health Reasons". A Resignation Letter is typically a formal document given to employers two weeks before an employee resigns from a role. Two weeks' notice letter template. Here is a template for a resignation letter that you can adapt for your own use: Resignation letter template.