Review these tips about how to write a nursing resignation letter, including the information that needs to be included and sample resignation letters. In this article, we will discuss how to write a resignation letter as a nurse and provide examples and tips.A nursing resignation letter serves as formal notice to your employer that you're leaving your position. It shows professionalism and courtesy. The complete guide to writing a nursing resignation letter with tips, examples, and templates. Goals of the nurse resignation letter, rules and tips for writing it, and a few sample letters that you can use. Please accept this letter as notice of my resignation effective immediately from my position as a department nurse. 137 votes, 60 comments. So that means cleaning up your desk, completing all the tasks that won't be carried over until the next term, etc. Nursing RN Resignation Letter Format ; Heading.