Generally, you may deduct up to 50 percent of your adjusted gross income, but 20 percent and 30 percent limitations apply in some cases. To qualify as a tax deduction, your charitable contribution needs to be given to a 503(c) organization.In many cases, charitable donations are tax-deductible. When you donate to a qualifying organization, you can deduct the amount from your taxable income. Donations of certain household items and clothing are often tax deductible when you file your income tax return. Here are some handy IRS tips for deducting charitable donations. When you bring items to one of our donation locations, you may fill out a paper donation form. Find out how taxpayers can claim deductions for clothing and property donations, and other noncash items. What is the cost basis for noncash charitable contributions? Tax deduction for donation of clothing.