1. First, register with the Ohio Secretary of State. Registration information as well as forms are available online(opens in a new window) or at (877) SOS-FILE.The 1st Stop Business Connection provides free statelevel information needed to get started or continue on your entrepreneurial journey. Information about starting, managing, and growing your business in Ohio. Ohio is the heart of business. Upon determining the type of business entity you would like to form, our office can assist you in the filing process. Starting a business in Ohio? We break down the steps to take, including registration, tax setup and choosing the right business structure. This step-by-step guide will show you how to register a business in Ohio if you're a new business owner or are registered from out of state. For most small businesses, registering your business is as simple as registering your business name with state and local governments.