The good news is that the majority of the costs of business travel can be tax deductible. However, the Internal Revenue Service (IRS) requires a few essentials.If you want to deduct your business expenses, you must complete Form 2106 and itemize your deductions. Travel expenses are the ordinary and necessary expenses of traveling away from home for your business, profession, or job. Per diem refers to a daily allowance for business travel expenses. If the travel is primarily for business reasons, then travel expenses would be deductible. Your travel expenses must be ordinary and relate to the business. Employees should not pay out of pocket for other employees' travel expenses. Thousand Oaks, Mooresville, there's Chicago in the house, we got people. Original receipts as support for expenses are expected.