When creating the Expense. Writing off travel expenses while away on business can save you hundreds of dollars per trip.Business travel expenses are tax deductible (for the most part), meaning you could lower the taxes you need to pay. Travel expenses are tax-deductible only if they were incurred to conduct business-related activities. All travel related expenses while you are on a business trip are tax deductible. You can also claim meals while traveling. If some of your travel involves business, you may be able to deduct travel expenses on your taxes. Experts explain how. What is business travel or a business trip? A woman in a window seat on an airplane checks her phone during a business trip.