Percutaneous closure of a patent foramen ovale (PFO) reduces the risk of recurrent cryptogenic stroke specifically in younger patients. In this heart surgery, the surgeon uses stitches to close the PFO .Patent foramen ovale closure is a procedure to close a hole in the heart. We use minimally invasive approaches to treat PFO without open-chest surgery. A PFO closure fills an opening between your heart's two upper chambers. This document addresses the transcatheter closure of patent foramen ovale and transcatheter or open left atrial appendage (LAA) closure.