Patent foramen ovale closure is a procedure to close a hole in the heart. We use minimally invasive approaches to treat PFO without open-chest surgery.In this heart surgery, the surgeon uses stitches to close the PFO . The foramen ovale is a hole in the wall between the left and right atria of every human fetus. This hole allows blood to bypass the fetal lungs. The Foramen Ovale is a small flaplike opening between the right and left heart chambers, which usually closes on its own during infancy. A PFO closure uses a medical device to close an opening between your heart's two upper chambers. You only need this opening as a fetus. The most common types of hole-in-heart problems are conditions like atrial septal defect (ASD) and patent foramen ovale (PFO).