Some studies have found that patent foramen ovales (PFOs) are more common in people with unexplained strokes and migraines with aura. This does not mean that everyone who has PFO will experience a stroke or mini-stroke.A heart condition called patent foramen ovale caused a stroke in this 18yearold. Doctors from three Northwell hospitals came together to save his life. The rate of recurrent stroke is relatively low. A patent foramen ovale is a small hole in the heart that may increase risk of stroke. Learn about how a PFO affect stroke risk.