The foramen ovale typically closes after birth, within the first year of life. In this heart surgery, the surgeon uses stitches to close the PFO .A newer technology allows for PFO closure with a simple stitch placed in the heart. If you have a PFO and low blood oxygen levels or an unexplained stroke, you may need a procedure to close the hole. The presence of a patent foramen ovale (PFO) is implicated in the pathogenesis of a number of medical conditions. PFO (Patent Foramen Ovale) and ASD (Atrial Septal Defect) are congenital heart conditions that affect the structure of the heart. Patent foramen ovale closure is a procedure to close a hole in the heart. We use minimally invasive approaches to treat PFO without open-chest surgery.