Arbitrage is the simultaneous purchase and sale of the same asset in different markets in order to profit from a difference in its price. Arbitrage Trading: Alameda uses the freshly minted USDT to buy cryptocurrencies at a lower price on one exchange.Arbitrage involves simultaneously purchasing and selling Assets in multiple markets to take advantage of price differences and generate profits. Buying and selling something at the same time, in different markets, in order to lock in a profit. What Is Crypto Arbitrage and How It Works: Complete Guide. Respondent Alameda Health System ("AHS") submits this.