An asset sale is the purchase of individual assets and liabilities, whereas a stock sale is the purchase of the owner's shares of a corporation. Unlike asset sales, stock sales do not require conveyances of each individual asset.Asset Sale lets buyers choose specific assets and liabilities; Stock Sale doesn't. The main difference between asset sales vs. Learn the tax implications for each type of sale. While an asset sale outshines a stock sale in company structure support, it loses a fair amount of points when it comes to tax implications.