An asset sale is the purchase of individual assets and liabilities, whereas a stock sale is the purchase of the owner's shares of a corporation. Asset Sale lets buyers choose specific assets and liabilities; Stock Sale doesn't.The main difference between asset sales vs. There are two primary ways to structure the taxable purchase and sale of an incorporated business. The parties may engage in an asset acquisition. Learn the tax implications for each type of sale. While an asset sale outshines a stock sale in company structure support, it loses a fair amount of points when it comes to tax implications.