An asset sale is the purchase of individual assets and liabilities, whereas a stock sale is the purchase of the owner's shares of a corporation. An "asset sale" refers to the acquisition of individual assets and liabilities.While an asset sale outshines a stock sale in company structure support, it loses a fair amount of points when it comes to tax implications. The main difference between asset sales vs. Asset Sale lets buyers choose specific assets and liabilities; Stock Sale doesn't. Learn the tax implications for each type of sale. A stock purchase is a complete purchase of a company, including all the assets and liabilities. Stock purchases thus have different tax outcomes. This guide will help you collect and remit local taxes correctly.