An asset sale is the purchase of individual assets and liabilities, whereas a stock sale is the purchase of the owner's shares of a corporation. With an asset sale, the buyer is buying the assets of the business.These assets will be identified in the purchase and sale agreement. The main difference between asset sales vs. A stock sale is when the owner sells off stock shares. An asset sale might not include all of the target's assets and potential liabilities. While an asset sale outshines a stock sale in company structure support, it loses a fair amount of points when it comes to tax implications. While stock sales occur between the shareholder (the business owner) and the buyer, asset sales occur between the company itself and the buyer. This guide will help you collect and remit local taxes correctly.