Subject: Request for Cancellation and Rescheduling of Appointment Dear [Recipient's Name], I hope this letter finds you in good health. I am writing this letter to inform you that due to an unforeseen event, I would like to cancel and reschedule my appointment with you at your office. I apologize for any inconvenience caused by this sudden change and I kindly request your assistance in accommodating my request. Firstly, I want to express my sincere apologies for any inconvenience caused by this cancellation. I understand the importance of adhering to schedules and maintaining professionalism, and I regret any disruption this may have caused to your daily activities. Unfortunately, a personal emergency has arisen unexpectedly, requiring my immediate attention and presence during the originally scheduled appointment. As a result, I am unable to attend the meeting as planned. I assure you that this is an exceptional circumstance, and I genuinely regret any inconvenience it may cause. Hence, I kindly request your understanding and willingness to reschedule our meeting. I greatly value the opportunity to discuss [mention topic/agenda of the appointment] with you and believe that our meeting can provide essential insights and solutions. Taking into consideration your busy schedule as well, I propose two alternative dates and times for the rescheduled appointment. I suggest [Proposed Date 1] and [Proposed Date 2], both of which are convenient for me and within your working hours. However, I am open to adjusting to any other available time slots that would suit your schedule better. I understand that your time is valuable, and I genuinely appreciate your flexibility and understanding in this matter. Please let me know at your earliest convenience if either of the proposed dates works for you, or if you would like to suggest another suitable time. Once again, I apologize for any inconvenience caused by this unfortunate situation. I look forward to your kind response and the opportunity to meet with you. Thank you for your understanding and cooperation. Sincerely, [Your Name] [Your Contact Information]