Dear [recipient's name], I am writing this letter to inform you that due to unforeseen circumstances, I am unable to keep my scheduled appointment on [date] at [time]. I apologize for any inconvenience this may cause and kindly request to cancel and reschedule the appointment at your earliest convenience. I completely understand the importance of maintaining commitments, and I value the opportunity to meet with you. However, due to [reason for cancellation], it is necessary for me to reschedule our appointment. I would be grateful if we could find a new mutually convenient date and time. I am available on [alternative dates], preferably between [time range]. Please let me know your availability, and I will make every effort to adjust my schedule accordingly. Once again, I apologize for any inconvenience caused by the need to cancel and reschedule our appointment. I assure you that I genuinely value this opportunity and look forward to meeting with you soon. Thank you for your understanding and cooperation. Should you need any further information or have any questions, please do not hesitate to contact me. Yours sincerely, [Your name] [Your contact information]