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In the calculation of the age-standardized rate, either one population is mathematically adjusted to have the same age structure as the other; or both populations are mathematically adjusted to have the same age structure as a third population, called the standard population 3.

"Crude Rate" refers to rates per 100,000 population. "Age-Adjusted Rate" refers to rates that are calculated as if the deaths occurred in a population with the same age structures. As the CDC website explains: "Some injuries occur more often among certain age groups than others.

Direct standardization is generally preferable because the populations of interest are compared to just one standard population, However, indirect standardization can be preferable with small sample sizes in different age groups. When we use direct standardization, we assume both groups have the same number of people.

"Crude Rate" refers to rates per 100,000 population. "Age-Adjusted Rate" refers to rates that are calculated as if the deaths occurred in a population with the same age structures. As the CDC website explains: "Some injuries occur more often among certain age groups than others.

Age-adjusted rates were calculated by dividing the expected number of deaths by the population (standard) and multiplying by 1,000.

A "standard" population distribution is used to adjust death and hospitalization rates. The age-adjusted rates are rates that would have existed if the population under study had the same age distribution as the "standard" population. Therefore, they are summary measures adjusted for differences in age distributions.

What is age-adjustment? Age-adjustment is a statistical process applied to rates of disease, death, injuries or other health outcomes which allows communities with different age structures to be compared.

A "standard" population distribution is used to adjust death and hospitalization rates. The age-adjusted rates are rates that would have existed if the population under study had the same age distribution as the "standard" population. Therefore, they are summary measures adjusted for differences in age distributions.

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Age-adjusted death rates eliminate the bias of age in the makeup of the populations being compared, thereby providing a much more reliable rate for comparison purposes. We will use a method of adjusting called "direct standardization." It consists of applying specific crude rates to a standard population.