Control Release For Free

What Is Controlled Release Technology? Controlled release technology is characterized by releasing drugs ing to a predictable and rational programed rate to achieve the optimal serum-drug concentration. This dosage form enhances the safety, efficacy, reliability, and convenience of drug therapy.

In addition to pills, the mechanism can also apply to capsules and injectable drug carriers (that often have an additional release function), forms of controlled release medicines include gels, implants and devices (e.g. the vaginal ring and contraceptive implant) and transdermal patches.

The key differences between controlled release and sustained release include: Sustained release is a slow release of medication over a period of time, whereas control release releases medication over time in correlation with concentration.

Controlled release are drug delivery system which maintain constant level of drug in blood and tissue for extended period of time. It implies A predictability and reproducibility in drug release kinetics In other words, the rate and duration are designed to achieve A desired concentration.

Osmotic controlled release works to pump medication out of the capsule, absorbing fluid from its surroundings as it passes through the body. This increased internal pressure then pushes the contents out through one or more precision holes in the membrane.

Examples include transdermal patches, implantable pumps, and intramuscular depot injections. This situation is very similar to an IV infusion, except that a portion of the drug can be broken down or metabolized prior to reaching the systemic circulation.

The controlled release formulations prepared by nanoparticles whose size varies from 10 to 1000nm facilitate the sustained release of drugs over time which in turn decreases the frequency of drug administration and improves patient compliance.

Extended-release dosage consists of either sustained-release (SR) or controlled-release (CR) dosage. SR maintains drug release over a sustained period but not at a constant rate. CR maintains drug release over a sustained period at a nearly constant rate.

Pharmaceutical companies use a variety of abbreviations to denote short- and long-acting medications. Commonly used abbreviations include CR for controlled release, SR for sustained release, ER for extended release, and IR for immediate release.

Controlled release drug delivery products are designed to release the active content in a predictable pattern in vivo over an extended time period albeit for some, faster release is desirable.