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How to Maximize Suboxone Absorption Check about taking Suboxone along with other medications. Some prescription and over-the-counter drugs and supplements can change the way Suboxone gets absorbed. ... Moisten your mouth. ... Let the drug dissolve. ... Don't help the drug dissolve. ... Stay quiet. ... Keep it closed.

?The recommended daily dose for maintenance is 16/4 mg. ?The maintenance dose ?is generally in the range of 4/1 mg buprenorphine/naloxone to 24/6 mg buprenorphine/naloxone per day depending on the individual patient. Dosages higher than this have not been demonstrated to provide any clinical advantage.?

Most patients stabilize on a dose of around 12-16mg which will be tapered down over the long term. It is possible that your doctor will prescribe you a higher dose of suboxone than this but ordinarily doses of over 32 mg are thought to be inadvisable as the effects of the drug begin to plateau.

A starting dose of buprenorphine can vary based on the setting and circumstance, generally between 2 mg and 8 mg. Buprenorphine generally alleviates opioid with- drawal symptoms within 20 to 40 minutes after the first dose.

For the maintenance phase of treatment, Suboxone film may be placed under your tongue or inside your cheeks to dissolve. The typical maintenance dosage of Suboxone ranges from 4 mg buprenorphine/1 mg naloxone up to 24 mg buprenorphine/6 mg naloxone, which is also the maximum dose.

Among patients newly initiating buprenorphine treatment for opioid use disorder, 59% of those prescribed the target daily dose of 16 milligrams recommended by the U.S. Food and Drug Administration and 53% of those prescribed the higher 24 mg daily dose discontinued treatment within 180 days.

The three-day rule permits practitioners to administer no more than one day's medication at a time for a maximum of three days, which cannot be renewed or extended. During the three-day period, the provider is expected to arrange for the patient's referral for treatment in a maintenance or detoxification program.